Case Study: Toradol Abuse

Tuesday, January 4, 2022 3:06:58 AM

Case Study: Toradol Abuse



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Case Study: Eddie's history of substance use

Introduction: Tramadol exhibits an effect profile similar to that of opioid agonists, and tramadol abuse seems to be a problem for a number of countries. The relationship between tramadol and sexual function appears to be controversial. Men with premature ejaculation PE may benefit from taking tramadol off label; however, these patients live "on a knife's edge" and are exquisitely sensitive to develop other sexual dysfunctions. Aim: To review the literature regarding the problem of tramadol abuse and its relationship with sexual function.

Main outcome measure: To define the supposed benefits and the potential risks of tramadol on different sexual functions including ejaculation, orgasm, erection, desire, and testosterone levels. Results: Although tramadol is thought to have low abuse and dependence potentials worldwide, its abuse has become a serious problem in many countries, particularly in the Middle East, Africa, and West Asia. The benefit of tramadol in PE was reported in 11 clinical trials, evaluated by 6 systematic reviews, 3 of which pooled data in a meta-analysis.

If you swallow broken, chewed, crushed, or dissolved extended-release preparations, you may receive too much tramadol at once instead and this may cause serious problems, including overdose and death. Do not allow anyone else to take your medication. Tramadol may harm or cause death to other people who take your medication, especially children. Your doctor or pharmacist will give you the manufacturer's patient information sheet Medication Guide when you begin treatment with tramadol and each time you refill your prescription.

Read the information carefully and ask your doctor or pharmacist if you have any questions. Tramadol is used to relieve moderate to moderately severe pain. Tramadol extended-release tablets and capsules are only used by people who are expected to need medication to relieve pain around-the-clock. Tramadol is in a class of medications called opiate narcotic analgesics. It works by changing the way the brain and nervous system respond to pain. Tramadol comes as a tablet, a solution liquid , an extended-release long-acting tablet, and an extended-release long-acting capsule to take by mouth. The regular tablet and solution are taken usually with or without food every 4 to 6 hours as needed.

The extended-release tablet and extended-release capsule should be taken once a day. Take the extended-release tablet and the extended-release capsule at about the same time of day every day. If you are taking the extended-release capsule, you may take it with or without food. If you are taking the extended-release tablet, you should either always take it with food or always take it without food. Do not take more medication as a single dose or take more doses per day than prescribed by your doctor. Taking more tramadol than prescribed by your doctor or in a way that is not recommended may cause serious side effects or death. Your doctor may start you on a low dose of tramadol and gradually increase the amount of medication you take, not more often than every 3 days if you are taking the solution, regular tablets or orally disintegrating tablets or every 5 days if you are taking the extended-release tablets or extended-release capsules.

If you are taking the solution, use an oral syringe or measuring spoon or cup to measure the correct amount of liquid needed for each dose. Do not use a regular household spoon to measure your dose. Ask your doctor or pharmacist if you need help getting or using a measuring device,. Do not stop taking tramadol without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking tramadol, you may experience withdrawal symptoms such as nervousness; panic; sweating; difficulty falling asleep or staying asleep; runny nose, sneezing, or cough; pain; hair standing on end; chills; nausea; uncontrollable shaking of a part of your body; diarrhea; or rarely, hallucinations seeing things or hearing voices that do not exist.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. If your doctor has told you to take tramadol regularly, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. Tramadol may cause other side effects.

Tell your doctor if you have any unusual problems while you are taking this medication. Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture not in the bathroom. It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily.

To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. In case of overdose, call the poison control helpline at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at While taking tramadol, you should talk to your doctor about having a rescue medication called naloxone readily available e.

Naloxone is used to reverse the life-threatening effects of an overdose. It works by blocking the effects of opiates to relieve dangerous symptoms caused by high levels of opiates in the blood. Your doctor may also prescribe you naloxone if you are living in a household where there are small children or someone who has abused street or prescription drugs. You should make sure that you and your family members, caregivers, or the people who spend time with you know how to recognize an overdose, how to use naloxone, and what to do until emergency medical help arrives.

Your doctor or pharmacist will show you and your family members how to use the medication. Ask your pharmacist for the instructions or visit the manufacturer's website to get the instructions. If symptoms of an overdose occur, a friend or family member should give the first dose of naloxone, call immediately, and stay with you and watch you closely until emergency medical help arrives. Your symptoms may return within a few minutes after you receive naloxone. If your symptoms return, the person should give you another dose of naloxone.

Additional doses may be given every 2 to 3 minutes, if symptoms return before medical help arrives. Keep all appointments with your doctor and laboratory. Your doctor may order certain lab tests to check your body's response to tramadol. Before having any laboratory test especially those that involve methylene blue , tell your doctor and the laboratory personnel that you are taking tramadol. Do not let anyone else take your medication. Tramadol is a controlled substance. Prescriptions may be refilled only a limited number of times; ask your pharmacist if you have any questions. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.

You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. Generic alternatives may be available.

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